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Antidepressants help relieve the symptoms of depression and anxiety. Common examples include selective serotonin reuptake inhibitors SSRIs, such as fluoxetine Prozac and serotonin and norepinephrine reuptake inhibitors SNRIs, such as duloxetine Cymbalta. They work by correcting chemical imbalances of neurotransmitters in the brain. Experts believe these are responsible for changes in mood and behavior. This article will cover the different types of antidepressants, how they work, their side effects, other uses, and alternative options.

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Common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping, and sexual dysfunction. Paroxetine was approved for medical use in the United States in and initially sold by GlaxoSmithKline. Paroxetine is primarily used to treat major depressive disorder, obsessive-compulsive disorder, post-traumatic stress disorder, social anxiety disorder, panic disorder. It could be used also for agoraphobia, generalized anxiety disorder, premenstrual dysphoric disorder and menopausal hot flashes. A variety of meta analyses have been conducted to evaluate the efficacy of paroxetine in depression. They have variously concluded that paroxetine is superior or equivalent to placebo and that it is equivalent or inferior to other antidepressants.

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