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This combination is often referred to as co-trimoxazole and works by targeting the bacteria that cause infections. Sulfamethoxazole is known as a sulphonamide and the other ingredient is considered to be similar to sulphonamides. Both of these ingredients act together to treat the symptoms of bacterial infections. Due to the risk of serious side effects, it is generally only used for serious infections. Doctors only tell patients to use it for infections which are less serious in nature when a tissue sample has confirmed that it the bacteria are susceptible to the active ingredients. This medicine is active against gram positive and gram negative bacteria, including infections occurring as a result of straphylococcus aureus, traphylococcus saprophyticus, listeria monocytogenes and various others.

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