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Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Indicated for the management of hypertension, to lower blood pressure, alone or in combination with other antihypertensive agents.
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Long-term treatment may be necessary to prevent relapse and chronic illness. Withdrawal of treatment must be cautious to prevent relapse.
Blood flow through the heart and round the body is maintained by contraction of the atria in unison followed by contraction of the ventricles in unison. The pulmonary and aortic valves close while the atria contract; the tricuspid and bicuspid valves close while the ventricles contract.
Authored by Dr. Michael J Thomas, MD