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Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. This is not a complete list of side effects and others may occur. Indomethacin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery coronary artery bypass graft, or CABG. Indomethacin may also cause stomach or intestinal bleeding, which can be fatal.
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Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. Indomethacin is also used to relieve pain from various other conditions. Indomethacin medication is known as non-steroidal anti-inflammatory drugs NSAIDs, and these drugs work by blocking the production of certain natural substances that may cause inflammation. This helps to reduce swelling and pain. If you plan on treating a chronic condition through this drug, discuss it with your doctor first.
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Taking indomethacin during the last 3 months of pregnancy may harm the unborn babyTell your doctor if you are pregnant or plan to become pregnant while using indomethacin. Indomethacin increases the negative effect of cyclosporine on kidney function and reduces the effect of furosemideLasixand thiazide diuretics because of prostaglandin inhibition.
Indomethacin is a white to yellow crystalline powder. Indomethacin has a pKa of 4. The suspension has a pH of 4. After observing the response to initial therapy with indomethacin, the dose and frequency should be adjusted to suit an individual patient's needs.
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