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It is the responsibility of healthcare professionals to decide, on an individual basis, the most appropriate treatment to suit the needs of the patient.
Atorvastatin a tor va stat' in is a potent, orally available inhibitor of hepatic 3-hydroxymethylglutaryl-coenzyme A HMG-CoA reductase, the major rate-limiting enzyme in cholesterol synthesis. The current primary indication for atorvastatin is the treatment of hypercholesterolemia in persons at high risk for coronary, cerebrovascular and peripheral artery disease. It is also available in combination with other cardiovascular agents such as amlodipine Caduet and generics. The recommended dose is 10 to 80 mg once daily based upon tolerability and lipid levels. Rare but potentially severe adverse events include liver injury, myopathy, rhabdomyolysis, and immune-mediated necrotizing myopathy. In summary analyses of large scale studies with prospective monitoring, ALT elevations above 3 times the upper limit of normal ULN occurred in 0.
Atorvastatin is used as an adjunct to nondrug therapies i. Atorvastatin in fixed combination with amlodipine is used in patients for whom treatment with both atorvastatin and a calcium-channel blocking agent i. Safety and efficacy of atorvastatin for primary prevention of cardiovascular disease have been established in several randomized, double-blind, placebo-controlled studies in patients without clinical evidence of CHD. Lipoprotein concentrations were lowered to levels similar to those observed with atorvastatin 10 mg daily in previous clinical studies. Treatment with atorvastatin did not reduce the risk of death from cardiovascular or noncardiovascular causes. However, atorvastatin therapy did not reduce overall mortality. Some clinicians state that the results of this study should be interpreted with caution due to the heterogeneity of enrolled patients i. Furthermore, because patients with atrial fibrillation or other cardiac sources of embolism were excluded from the study, it is not known whether the observed benefits of atorvastatin apply to ischemic strokes of cardioembolic origin.
The FDA did not go far enough in restricting the use of high doses of the cholesterol drug Zocor, and approval for 80 mg simvastatin medications should have been withdrawn according to Public Citizen. It is supplied by Pfizer U. Objective: Primary objective was to compare the effects of atorvastatin 40mg vs 80mg on LDL-C in Indian patients with atherosclerotic dyslipidemia. Lipitor is generic lipitor 80 mg to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors. Answers is the place to go to get the answers you need and to ask the questions you want. Want this question answered?
Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to zyprexa cost price abnormal lipid levels. Atorvastatin was patented in, and approved for medical use in the United States in The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease: 9. Statins predominantly simvastatin have been trialled in combination with fibrates to manage dyslipidemia in patients who also have type 2 diabetes, and a high cardiovascular disease risk, however, there is limited clinical benefit noted for most cardiovascular outcomes 35 While many short half-lives statin medications should be administered in the evening for optimal effect, atorvastatin can be dosed at any time of day due to its long half-life profile, as long as it is continually dosed once daily at the same time to enhance better adherence.
Government of Newfoundland and Labrador. Strength This refers to the amount of the active medicinal ingredient e.
Consult your doctor for more details. Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of this medication in your bloodstream.
Treatment of primary dysbetalipoproteinemia Type III not adequately responsive to diet. Adjunct to other lipid-lowering treatments or when these are unavailable, in homozygous familial hypercholesterolemia to reduce total-C and LDL-C.
Food and Drug Administration approved the medication in Its active ingredient is atorvastatin calcium.
Lipitor is a white, elliptical film coated tablet containing atorvastatin calcium. Atorvastatin is indicated as an adjunct to diet for the treatment of patients with elevated total cholesterol total-C, low density lipoprotein cholesterol LDL-C, apolipoprotein B apo B, and triglycerides TG and to increase high density lipoprotein cholesterol HDL-C in patients with primary hypercholesterolemia heterozygous familial and non-familial hypercholesterolemia, combined mixed hyperlipidemia Fredrickson Types IIa and IIb, elevated serum TGlevels Fredrickson Type IV, and for patients with dysbetalipoproteinemia Fredrickson Type III who do not respond adequately to diet.
Lipitor is a medication used to reduce lipid and cholesterol levels in certain groups of patients. Lipitor is a medication that contains atorvastatin calcium. Lipitor is also frequently used in patients with hypercholesterolemia to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C, in patients with high triglyceride levels in the serum, and various other situations. Lipitor is an inhibitor of 3-hydroxymethylglutaryl-coenzyme A HMG-CoA reductase and is also similar to Livalo, rosuvastatin Crestor and simvastatin. Before using Lipitor tablets and while using Lipitor, patients should utilize a cholesterol-lowering diet. Lipitor dosage adjustments usually do not need to be made for people with renal insufficiency.
Atorvastatin 80 cost Side Effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Buy repeats of your atorvastatin online with ZAVA. Here are answers to some frequently asked questions about drug prices and atorvastatin. Atorvastatin coupons may also be available for people who cannot afford to purchase the medication.