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This non-approvable letter was due to safety concerns of an increased risk of cardiovascular events including heart attack and stroke and questions on the benefit-risk ratio in patients taking Arcoxia. Merck will continue to market Arcoxia outside the United States. Your doctor will want discuss your treatment with Arcoxia from time to time. It is important that you use the lowest dose that controls your pain and you should not take Arcoxia for longer than necessary. This is because the risk of heart attacks and strokes might increase after prolonged treatment, especially with high doses.
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There are several procedures which can be used in pain management. The various procedures vary from conservative non-invasive treatments to surgery.
Tell your doctor if you have ever had an allergic reaction to any other anti-inflammatory medicine. By blocking the effect of COX-2 enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.
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