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ARAVA is a pyrimidine synthesis inhibitor indicated for the treatment of adults buy arava usa active rheumatoid arthritis. ARAVA is contraindicated for use in pregnant women because of the potential for fetal harm. Teratogenicity and embryo-lethality occurred in animals administered leflunomide at doses lower than the human exposure level.

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Leflunomide, sold under the brand name Arava among others, is an immunosuppressive disease-modifying antirheumatic drug DMARD, 7 used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Rheumatoid arthritis and psoriatic arthritis are the only indications that have received regulatory approval. Food and Drug Administration in The dose-limiting side effects are liver damage, lung disease and immunosuppression.

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From traditional pain medication to natural remedies, there are many treatment options to fit your needs. Just as there are many types of pain, there are also many ways to treat arthritis pain. Disease-modifying medications. Fortunately, a variety of medications — many developed in recent decades or years — make disease control possible. Drugs that can control the disease process include

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Do not take leflunomide if you are pregnant or plan to become pregnant. Leflunomide may harm the fetus. You should not begin taking leflunomide until you have taken a pregnancy test with negative results and your doctor tells you that you are not pregnant. You must use an effective method of birth control before you begin taking leflunomide, during your treatment with leflunomide, and for mestinon 60 mg valeant years after treatment.

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