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Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Duloxetine is used to treat major depressive disorder in adults. Duloxetine is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes diabetic neuropathy. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Your doctor should check your progress at regular visits.
Bleeding disorders; cardiac disease; elderly; history of mania; history of seizures; hypertension avoid if uncontrolled ; raised intra-ocular pressure; susceptibility to angle-closure glaucoma. Anxiety; appetite decreased; constipation; diarrhoea; dizziness; drowsiness; dry mouth; fall; fatigue; flushing; gastrointestinal discomfort; gastrointestinal disorders; headache; muscle complaints; nausea; pain; palpitations; paraesthesia; sexual dysfunction; skin reactions; sleep disorders; sweat changes; tinnitus; tremor; urinary disorders; vision disorders; vomiting; weight changes; yawning. Apathy; arrhythmias; behaviour abnormal; burping; chills; concentration impaired; disorientation; dysphagia; ear pain; feeling abnormal; gait abnormal; haemorrhage; hepatic disorders; hyperglycaemia; increased risk of infection; malaise; menstrual disorder; movement disorders; mydriasis; peripheral coldness; photosensitivity reaction; postural hypotension; suicidal behaviours; syncope; taste altered; temperature sensation altered; testicular pain; thirst; throat tightness; vertigo. Angioedema; cutaneous vasculitis; dehydration; galactorrhoea; glaucoma; hallucination; hyperprolactinaemia; hypertensive crisis; hyponatraemia; hypothyroidism; mania; menopausal symptoms; oral disorders; seizure; serotonin syndrome; SIADH; Stevens-Johnson syndrome; urine odour abnormal. Toxicity in animal studies—avoid in patients with stress urinary incontinence; in other conditions use only if potential benefit outweighs risk. Risk of neonatal withdrawal symptoms if used near term.
Sort by: Most recent Helpfulness Most Recent. Mar 31, Started Jul 01, Effectiveness. Never taken as prescribed. Jul 24, Started Jul 01, Effectiveness. Moderate for major depressive disorder.
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Cymbalta, also known by its generic name of duloxetine, is a type of antidepressant. Cymbalta may also be prescribed off-label for other anxiety disorders, such as panic disorder cymbalta 30 mg social anxiety disorder. Generalized anxiety disorder is a type of anxiety disorder characterized by Excessive and persistent worry which lasts for at least six months. Perceiving everyday situations as threatening. Heart palpitations and trembling.
The starting and recommended maintenance dose is 60 mg once daily with or without food. After consolidation of the antidepressive response, it is recommended to continue treatment for several months, in order to avoid relapse. The recommended starting dose in patients with generalised anxiety disorder is 30 mg once daily with or without food. The starting and recommended maintenance dose is 60 mg daily with or without food. The plasma concentration of duloxetine displays large inter-individual variability see section 5.
Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States in Duloxetine is recommended as a first-line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain Therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies. Food and Drug Administration approved duloxetine to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. In 4 clinical trials of duloxetine for the treatment of MDD, sexual dysfunction occurred significantly more frequently in patients treated with duloxetine than those treated with placebo, and this difference occurred only in men. The suicide attempt rate in the SUI study population based on 9, patients was calculated to be per, person years.
Duloxetine and 60 mg capsules can be prescribed on the Pharmaceutical Benefit Scheme PBS for people with a major depressive disorder. The 30 mg capsule is listed as a month's supply with no repeats. People with renal impairment who require this strength on an ongoing basis will need an authority for any repeats. The PBAC had previously accepted as plausible the argument that the discontinuation rate with duloxetine could be reduced by slower dose titration. However, it remained concerned that in trials twice as many people stopped taking duloxetine because of adverse events as stopped taking venlafaxine.
I tried several different medications for depression but none helped until Duloxetine. It's been 3 years with 2 and a half of those years at mg per day. Easy to take, no side effects apart from if your late in taking your dose you'll feel like your upside down, falling and every little noise makes you jump. So be vigilant in taking them on time. Here's hoping the brain zaps dont get me too much. This drug worked the best for me.
Distributor: Zuellig Pharma. Each capsule contains 30 mg of duloxetine as hydrochloride. Each capsule contains 60 mg of duloxetine as hydrochloride. Excipient s with known effect 60 mg: each capsule may contain up to mg sucrose. Pharmacotherapeutic group: Other antidepressants.