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Spironolactone belongs to the class of medications known as diuretics water pills. It is used to treat edema fluid retention that occurs with congestive heart failure, cirrhosis of the liver, and nephrotic syndrome. It is also used to treat high blood pressure and to diagnose and treat primary hyperaldosteronism a condition where too much aldosterone is produced by the adrenal glands. Spironolactone can also be used to treat or prevent hypokalemia too little potassium in the body when other methods are not appropriate. Spironolactone works by making the body lose excess water and salt but reduces the loss of potassium from the body.
Aldactone spironolactone is a potassium-sparing diuretic water pill that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. You should use Aldactone with caution if you have kidney problems, high levels of potassium in your blood, Addison's disease, if you are unable to urinate, or if you are also taking eplerenone. Aldactone has caused tumors in animals but it is not known whether this could occur in people. Do not use this medicine for any condition that has not been checked by your doctor. Your doctor should decide whether you take Aldactone if you are pregnant. Take Aldactone exactly as prescribed by your doctor.
Unnecessary use of this drug should be avoided. Inactive ingredients include calcium sulfate, corn starch, flavor, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide. Establishing the diagnosis of primary hyperaldosteronism by therapeutic trial. Long-term maintenance therapy for patients with discrete aldosterone -producing adrenal adenomas who are judged to be poor operative risks or who decline surgery. Long-term maintenance therapy for patients with bilateral micro or macronodular adrenal hyperplasia idiopathic hyperaldosteronism. For the management of edema and sodium retention when the patient is only partially responsive to, or is intolerant of, other therapeutic measures.
Spironolactone is a powerful potassium-sparing diuretic that inhibits the binding of aldosterone to mineralocorticoid receptors in many tissues, including epithelial cells of the distal convoluted tubule and collecting duct. Contraindications —hypersensitivity to drug or class, anuria, renal insufficiency, hyperkalemia. Caution —hepatic or renal dysfunction, hyponatremia, diabetes mellitus. Spironolactone should be used during pregnancy and lactation only if the benefit justifies the potential perinatal risk. Spironolactone can be used in combination with other diuretics, primarily furosemide, to produce additional diuresis generally a mild increase or to decrease potassium excretion. In addition, as an aldosterone antagonist, spironolactone is aldactone spironolactone 25 mg a neuroendocrine modulator aldosterone receptor blocker.
Spironolactone is used in combination with other medicines to trileptal 300 mg tablet high blood pressure hypertension and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Spironolactone is also used to lessen the need for hospitalization for heart failure. Spironolactone is a potassium-sparing diuretic water pill. It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.
It comes as an oral tablet and an oral suspension a kind of liquid mixture. Spironolactone oral tablet is available as the brand-name drug Aldactone and as a generic drug. This drug is used to reduce swelling from liver disease and nephrotic syndrome a kidney problem. These drugs are often used to treat similar conditions. Spironolactone works by blocking aldosterone activity. Aldosterone is a chemical made by the body that can cause water retention.
If you are worried about using this medicine, speak to your doctor or pharmacist. Aldactone contains the active ingredient spironolactone.
Salt Composition: Spironolactone. Aldactone 25mg tablet contains the active constituent spironolactone, which belongs to the class of potassium-sparing diuretics.
It is used to treat fluid accumulation in the tissues due to heart disorders and in the abdominal cavity, severe heart failure NYHA III-IV, and certain kidney disorders. Fluid regularly drains into body tissues from the blood.
ALDACTONE is indicated as add-on therapy for the treatment of hypertension, to lower blood pressure in patients who are not adequately controlled on other agents. Patients who develop hyperkalemia on 25 mg once daily may have their dosage reduced to 25 mg every other day see Warnings and Precautions 5. Dosage can be titrated at two-week intervals. In patients with cirrhosis, initiate therapy in a hospital setting and titrate slowly see Use in Specific Populations 8. When given as the sole agent for diuresis, administer for at least five days before increasing dose to obtain desired effect. For patients who are considered unsuitable for surgery, ALDACTONE can be used as long-term maintenance therapy at the lowest effective dosage determined for the individual patient.
Spironolactone is used to treat fluid retention oedema caused by liver disease, kidney problems or heart failure. Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless or your legs feel puffy. Spironolactone prevents a build-up of fluid in your body by increasing the amount of urine your kidneys produce. Spironolactone is known as a potassium-sparing diuretic. Unlike some other diuretics, it does not cause your body to lose potassium.