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Linezolid is used to treat different types of bacterial infections. General properties Linezolid is a synthetic, antibacterial agent that belongs to a new class of antimicrobials, the oxazolidinones. Linezolid selectively inhibits bacterial protein synthesis via a unique mechanism of action. The Zyvox price accredited production data furthermore in the treatment of behavior towards superficial epidermis and epidermis arrangement transmissions.
Each mL contains 2 mg of linezolid. Nosocomial pneumonia caused by Staphylococcus aureus methicillin -susceptible and -resistant isolates or Streptococcus pneumoniae. Community-acquired pneumonia caused by Streptococcus pneumoniae, including cases with concurrent bacteremia, or Staphylococcus aureus methicillin-susceptible isolates only. Complicated skin and skin structure infections, including diabetic foot infections, without concomitant osteomyelitis, caused by Staphylococcus aureus methicillin-susceptible and -resistant isolates, Streptococcus pyogenes, or Streptococcus agalactiae. Uncomplicated skin and skin structure infections caused by Staphylococcus aureus methicillin-susceptible isolates only or Streptococcus pyogenes.
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Linezolid, an antibiotic approved for the treatment of other bacterial infections—but not approved by any regulatory authority for the treatment of TB—can be an important drug in a regimen to treat drug-resistant TB when few other options exist. In one small trial, 41 people with XDR-TB on individualized regimens were randomized to receive mg daily of linezolid, either immediately or after two months. TB programs and doctors can monitor for and manage these side effects as part of routine care. Reducing the dose or changing the dosing schedule of linezolid may help: lowering doses to mg per day or less may reduce side effects without making the drug less effective. With recent efforts to diagnose more drug-resistant TB, and the approval of new treatments, bedaquiline and delamanid, demand for important companion drugs such as linezolid should increase.
Linezolid is used to treat infections, including pneumonia, and infections of the skin. Antibiotics such as linezolid will not work for colds, flu, and other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Authored by Dr. Scott Shapiro, MD