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TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring.
Imipramine belongs to a group of drugs known as tricyclic antidepressants, or TCAs. While TCAs have been on the market for decades, scientists are still unclear as to exactly how these drugs work. Like all antidepressants, imipramine carries a black-box warning because some people may become severely depressed and suicidal while taking the drug. Talk to your doctors about the risks of suicide ideation before taking imipramine or any other antidepressant. Also, don't expect to notice a big difference in your mood when you first start taking imipramine.
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Relevant articles were abstracted by a trained physician researcher. Co-ingestion of additional substances could require different referral and management recommendations depending on their combined toxicities. Recommendations are in chronological order of likely clinical use. The grade of recommendation is in parentheses. Ingestion of a TCA in combination with other drugs might warrant referral to an emergency department. The ingestion of a TCA by a patient with significant underlying cardiovascular or neurological disease should cause referral to an emergency department at a lower dose than for other individuals. Because of the potential severity of TCA poisoning, transportation by EMS, with close monitoring of clinical status and vital signs en route, should be considered Grade D. Prehospital activated charcoal administration, if available, should only be carried out by health professionals and only if no contraindications are present. These patients do not need referral to an emergency department facility Grade C. A wide-complex arrhythmia with a QRS duration longer than msec is an indicator that the patient should be immediately stabilized, given sodium bicarbonate if there is a protocol for its use, and transported to an emergency department Grade B.
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Tofranil Generic Name: imipramine is a tricyclic antidepressant taken orally that is primarily used to treat depression in adolescents and adults. It can also be used to treat bed-wetting in children age six and older. It is not considered a controlled substance by the FDA. If you have questions, ask your doctor or pharmacist before you begin taking the medication. Do not drink alcohol, or take barbituates or other central nervous system depressants while taking this drug. The optimal dosage varies patient by patient.
From: Handbook of Neuroendocrinology, Imipramine Figure 3 is a TCA. Imipramine is comprised of a tricyclic nucleus including two phenyl rings and a central cycloheptadien ring. Caution —history of seizure, glaucoma, CAD, thyroid disease, hepatic dysfunction, suicide risk. Imipramine should be used during pregnancy and lactation only if the benefit justifies the potential perinatal risk.
Availability Capsules: 75 mg, mg, mg, mg pamoate Tablets: 10 mg, 25 mg, 50 mg hydrochloride Indications and dosages Endogenous depression Adults: 75 to mg P. Imipramine pamoate C61H64N4O6 CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities.
Action Inhibits reuptake of norepinephrine and, to a lesser degree, serotonin in CNS. Unlabeled use s: Treatment of chronic pain, panic disorder, eating disorders bulimia nervosa, and facilitation of cocaine withdrawal.
Imipramine HCl immediate-release tablets: Initial doses are often given at bedtime, and as doses are titrated upward, divided dosing is usually necessary to adjust for tolerability. For enuresis in children, the daily dose is usually given 1 hour prior to anticipated bedtime.
Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants TCA. In deciding to use a medicine, the risks of taking the medicine must be weighed against the tofranil pm 75 mg it will do. This is a decision you and your doctor will make. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Buy tofranil pm Looking for a tofranil? These employees can finally keep their condition private and continue using their jobs after they use pharmacy finder. Tofranil imipramine is a medication treatment option for depression in adults or nighttime bedwetting in children 6 years and older. Drug Uses Tofranil is used for treating depression. Abilify aripiprazole is good for treating psychosis and mania, and can help with depression.