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Use: Alone or in combination with other antihypertensive drugs in the treatment of hypertension.
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Blocks calcium - dependent contractions in cardiac and cardizem 420 mg smooth muscle leading to vasodilation; slows cardiac conduction through the AV node. Non-acute setting or maintenance: to mg PO daily. Elderly: Initiate dosage at the lower end of the adult range.
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You should not use diltiazem if you have very low blood pressure, a serious heart condition such as sick sinus syndrome or AV block unless you have a pacemaker, or if you have recently had a heart attack and you have a build-up of fluid in your lungs. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
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Your medication may look different. If you have questions, ask your pharmacist. Generic name: Diltiazem sustained-action - oral. Pronunciation dill-TIE-uh-zem. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional.
What is diltiazem, and how does it work mechanism of action? Diltiazem is a drug that is used for treating heart pain angina, high blood pressure, and abnormal heart rhythms. It is the entry of calcium into these cells that causes the cells to contract, allowing the heart to pump blood, and the arteries to narrow. By blocking the entry of calcium, diltiazem decreases the force of contraction of the heart and its rate of contraction. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen dilate.
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Authored by Dr. Nancy Jane Hamilton, DDS