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Phosphate binders are used to decrease the absorption of phosphate from food in the digestive tract. They are used when there is an abnormally high blood phosphate level hyperphosphatemia which can be caused by impaired renal phosphate excretion or increased extracellular fluid phosphate loads. When taken regularly with meals, phosphate binders lower the concentration of phosphate in serum. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Phosphate binders What are Phosphate binders? Tukysa Tukysa tucatinib is a kinase inhibitor indicated in combination with Koselugo Koselugo selumetinib is an inhibitor of mitogen-activated protein kinase
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It is likely someone with Stage 4 CKD will need dialysis or a kidney transplant in the near future. The study, which was presented at the International Society of Nephrology meeting in Copenhagen, Denmark, October 13, was a prospective, multi-centre, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of PhosLo in Stage 4 CKD patients. When the application is granted, PhosLo will provide nephrologists another therapeutic option that will allow them to start treatment of hyperphosphatemia earlier. Often, calcium levels are lowered hypocalcemia due to precipitation of phosphate with the calcium in tissues. It is associated with secondary hyperparathyroidism and commonly seen in chronic renal failure. High phosphate levels can be avoided with phosphate binders and dietary restriction of phosphate.