Besides depression, amitriptyline can be used off-label to treat post-herpetic neuralgia a condition that occurs after having shingles, attention deficit hyperactivity disorder ADHD, and certain eating disorders. Other drugs in this class are desipramine Norpramin, nortriptyline Pamelor, Aventyl, and imipramine Tofranil.
However, your pharmacist may have suggested a different schedule that is more appropriate for you. Take it regularly and continuously to maintain its beneficial effects. It is not advisable to stop using this product suddenly, particularly if you have been on it for several weeks. If you are considering stopping the medication, talk to your pharmacist first. If you forget a dose, take it as soon as you remember -- unless it is almost time for your next dose. In that case, skip the missed dose.
What is amitriptyline, and how does it work mechanism of action? Other drugs in the same class include Individuals with depression may have an imbalance in neurotransmitters, chemicals that nerves make and use to communicate with other nerves. Like all TCAs, amitriptyline increases levels of norepinephrine and serotonin, two neurotransmitters, and blocks the action of acetylcholine, another neurotransmitter. It is believed that by restoring the balance of these different neurotransmitters in the brain that depression is alleviated for example, the mood is elevated. Amitriptyline was approved by the FDA in May What are the uses for amitriptyline?
This medicinal product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis. Dosage should be initiated at a low level and increased gradually, noting carefully the clinical response and any evidence of intolerability. Initially 25 mg 2 times daily 50 mg daily. If necessary, the dose can be increased by 25 mg every other day up to mg daily divided into two doses. The daily dose may be increased up to mg — mg divided into two doses, depending on individual patient response and tolerability. Amitriptyline should not be used in children and adolescents aged less than 18 years, as long term safety and efficacy have not been established see section 4. The antidepressant effect usually sets in after 2 - 4 weeks. Treatment with antidepressants is symptomatic and must therefore be continued for an appropriate length of time usually up to 6 months after recovery in order to prevent relapse.
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A, Low back pain intensity was measured using the mm visual analog scale greater pain intensity is indicated by higher numbers. B, Low back disability was assessed using the Roland Morris Disability Questionnaire points; greater levels of disability are reflected by higher numbers. Error bars indicate standard error of the mean. Responder analyses examining clinical meaningful change in low back pain and disability based on treatment with low-dose amitriptyline or an active comparator. Percentage of participants with moderate to severe side-effects based on treatment with low-dose amitriptyline or an active comparator. Question Is a low-dose tricyclic antidepressant effective in the treatment of chronic low back pain?
Contains the active ingredient amitriptyline as hydrochloride. This leaflet answers some common questions about amitriptyline. It does not take the place of talking to your doctor or pharmacist. Ask your doctor or pharmacist All medicines have risks and benefits.
Amitriptyline oral tablet is not available as a brand-name drug. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Amitriptyline works on your central nervous system to increase the level of certain chemicals in your brain, which improves your depression. Amitriptyline can cause dizziness and drowsiness during the first few hours after you take 25 mg amitriptyline. If you notice drowsiness while you take this drug, your doctor may have you take your dose at bedtime.
Amitriptyline belongs to a family of medications known as tricyclic antidepressants. It is used to treat depression.
Amitriptyline hydrochloride, also known as Elavil, is a tricyclic antidepressant TCA with analgesic properties, widely used to treat depression and neuropathic pain 5. It was originally approved by the FDA in and manufactured by Sandoz
Amitriptyline is also used to treat migraine and certain types of nerve pain. When deciding whether or not to take amitriptyline during pregnancy it is important to weigh up how necessary amitriptyline is to your health against the possible risks to you or your baby, some of which will depend on how many weeks pregnant you are.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Other side effects not listed may also occur in some patients.
Amitriptyline is an antidepressant medicine. It's used to treat low mood and depression. It comes as tablets and as a liquid. Amitriptyline is also used for some types of pain and to prevent migraines. Find out more about amitriptyline for pain and migraine.
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