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Olanzapine belongs to group of medications known as antipsychotic agents.
Given the increasing use of atypical antipsychotics in psychiatric populations and the very limited data concerning the safety of such drugs, we examined the available data on olanzapine in untreated overdose situations. Despite the complexities and limitations of postmortem data analysis, 29 deaths were identified where an overdose of olanzapine was either the principal cause of toxicity or a significant contributor in combined toxicity. Olanzapine is associated with toxicity in certain overdose situations, but evidence of any relation is limited and likely influenced by the higher rates of cardiovascular disease and sudden death in subjects with schizophrenia. Early signal detection and effective notification processes are crucial in the event that serious adverse effects do occur. Olanzapine is an atypical antipsychotic of the thienobenzodiazepine class.
Common side effects include weight gain, movement disorders, dizziness, feeling tired, constipation, and dry mouth. Zyprexa olanzapin 15 mg was patented in and approved for medical use in the United States in The first-line psychiatric treatment for schizophrenia is antipsychotic medication; with olanzapine being one such medication. National Institute for Health and Care Excellence, the British Association for Psychopharmacology, and the World Federation of Societies for Biological Psychiatry suggest that there is little difference in effectiveness between antipsychotics in prevention of relapse, and recommend that the specific choice of antipsychotic be chosen based on a person's preference and the drug's side effect profile. Agency for Healthcare Research and Quality concludes that olanzapine is not different from haloperidol in the treatment of positive symptoms and general psychopathology, or in overall assessment, but that it is superior for the treatment of negative and depressive symptoms.
Olanzapine oh-LAN-za-peen is an atypical antipsychotic medicine which can be used to treat mania, schizophrenia and bipolar disorder. Always talk to your doctor about your situation and whether this medication is for you. Elizabeth tells her story of taking olanzapine and sertraline for anorexia. Medication type: atypical antipsychotic. If you are 18 or over, the doctor can prescribe olanzapine for you as a licensed medicine for mania, schizophrenia and bipolar disorder.
Zyprexa olanzapine is an atypical antipsychotic medication used to treat symptoms of psychotic conditions such as bipolar disorder manic depression and schizophrenia. It used to treat adults and children who are at least 13 years old. Olanzapine may also be used to prevent vomiting or nausea caused by chemotherapy, a cancer drug treatment.
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Active ingredient name: Olanzapine. Type of medication: Atypical antipsychotic. This short-acting intramuscular injection is approved for use in Zyprexa olanzapin 15 mg and is used primarily for acute situations.
All FDA black box warnings are at the end of this fact sheet. Olanzapine is a medication that works in the brain to treat schizophrenia. Olanzapine rebalances dopamine and serotonin to improve thinking, mood, and behavior. Symptoms of schizophrenia include
Olanzapine belongs to group of medications known as antipsychotic agents. Schizophrenia zyprexa olanzapin 15 mg cause symptoms such as hallucinations e. People with this condition may also feel depressed, anxious, or tense.
Zyprexa IntraMuscular is indicated for the treatment of acute agitation associated with schizophrenia and bipolar I mania. Oral Zyprexa and fluoxetine in combination is indicated for the treatment of depressive episodes associated with bipolar I disorder. Oral Zyprexa and fluoxetine in combination is indicated for the treatment of treatment resistant depression major depressive disorder in patients who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode.
This drug has a boxed warning. Black box warnings alert doctors and patients about drug effects that may be dangerous. Olanzapine may be used as part of a combination therapy. This means you may need to take it with other medications, zyprexa olanzapin 15 mg as lithium, valproate, or fluoxetine. Olanzapine is used to treat schizophrenia and bipolar I disorder.
It may also be used in combination with other medication zyprexa olanzapin 15 mg treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Talk to the doctor about the risks and benefits of treatment especially when used in teenagers.
Indicated for depressive zyprexa olanzapin 15 mg associated with bipolar I disorder in combination with fluoxetine. Safety of coadministered doses greater than olanzapine 18 mg with fluoxetine 75 mg have not been evaluated. Off-label use for prevention of chemotherapy associated nausea or vomiting in combination with 5-HT3 antagonist and dexamethasone N Engl J Med ; Breakthrough nausea and vomiting: mg PO qDay for 3 days, when not used for acute and delayed emesis prevention.
Caution: Monitor for signs and symptoms of post injection syndrome for at least 3 hours after administering olanzapine depot injection. The Pharmaceutical Benefits Advisory Committee recommended olanzapine depot injection for listing consistent with the listings of other long-acting antipsychotic injections for the treatment of schizophrenia. It is approved for maintenance treatment of schizophrenia in adults sufficiently stabilised during acute treatment with oral olanzapine. The PBS listing of olanzapine depot injection provides an additional long-acting atypical antipsychotic option to risperidone IM long-acting injection, the only other depot atypical antipsychotic approved and PBS listed for maintenance treatment in schizophrenia.
Learn about the medical, dental, pharmacy, behavioral, and voluntary benefits your employer may offer. Olanzapine is an antipsychotic medication that is used to treat psychotic conditions such as schizophrenia and bipolar disorder manic depression in adults and children at least 13 years old. Olanzapine is also used together with fluoxetine Prozac to treat episodes of depression in adults and children at least 10 years old who have bipolar I disorder. Taking antipsychotic medicine in the zyprexa olanzapin 15 mg 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away.
Olanzapine is a dopamine D 1, D 2, D 4, 5-HT 2, histamine- 1-, and muscarinic-receptor antagonist. Acute myocardial infarction; bradycardia; recent heart surgery; severe hypotension; sick sinus syndrome; unstable angina. An ECG may be required, particularly if physical examination identifies cardiovascular risk factors, personal history of cardiovascular disease, or if the patient is being admitted as an inpatient. See also Prescribing in the elderly.
However, these interactions are unlikely with topical application. Systemic administration of imidazoles is often necessary for tinea of the nail. Systemic use of antifungal drugs is considered in Chapter Terbinafine displays a broad spectrum of antifungal activity at low concentrations. Its mechanism of action is zyprexa olanzapin 15 mg interfering with the synthesis of ergosterol in the fungal cell membrane.
Authored by Dr. Linda Suriyakham, PHD