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Indicated for depressive episodes associated with bipolar I disorder in combination with fluoxetine. Safety of coadministered doses greater than olanzapine 18 mg with fluoxetine 75 mg have not been evaluated. Off-label use for prevention of chemotherapy associated nausea or vomiting in combination with 5-HT3 antagonist and dexamethasone N Engl J Med ; Breakthrough nausea and vomiting: mg PO qDay for 3 days, when not used for acute and delayed emesis prevention. Safety of coadministered doses greater than olanzapine 12 mg with fluoxetine 50 mg have not been in pediatric clinical studies.
Olanzapine is an antagonist with moderate affinity binding for serotonin 5HT3 and muscarinic M, respectively. Contraindicated in patients with a known hypersensitivity to the product. May exacerbate, possibly precipitate, diabetes mellitus, low white blood cell count or liver dysfunction. Caution in galactosemia and phenylketonuria due to excipients. Commonly seen side effects include weight gain, hypertriglyceridemia, hypercholester-olemia, drowsiness. Less commonly seen are postural hypotension, xerostomia, insomnia, constipation, dyspepsia, hyperprolactinemia, hyperglycemia, accidental injury and peripheral edema.
Bipolar disorder: as monotherapy or with lithium or valproate for short-term use in acute mixed or manic episodes, or for maintenance. In combination with fluoxetine: depressive episodes associated with bipolar I disorder, or treatment resistant depression TRD. Concomitant lithium or valproate: initially 10mg once daily. Risk of hypotension, hepatic impairment, slow metabolizers, or sensitive to olanzapine: initially olanzapine 2. Dose adjustments: see full labeling. Zydis: Dissolve in mouth and swallow with or without fluids.
Zyprexa IntraMuscular is indicated for the treatment of acute agitation associated with schizophrenia and bipolar I mania. Oral Zyprexa and fluoxetine in combination is indicated for the treatment of depressive episodes associated with bipolar I disorder. Oral Zyprexa and fluoxetine in combination is indicated for the treatment of treatment resistant depression major depressive disorder in patients who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode. Zyprexa olanzapine is an atypical antipsychotic. The mechanism of action of olanzapine, in the listed indications is unclear.
What is olanzapine, and how does it work mechanism of action? Olanzapine is a drug that is used to treat schizophrenia and acute manic episodes associated with bipolar I disorder. Olanzapine belongs to a drug class known as atypical antipsychotics. Other members of this class include clozapine Clozaril, risperidone Risperdal, aripiprazole Abilify and ziprasidone Geodon. The exact mechanism of action of olanzapine is not known.
Zyprexa olanzapine is an atypical antipsychotic medication used to treat symptoms of psychotic conditions such as bipolar disorder manic depression and schizophrenia. It used to treat adults and children who are at least 13 years old. Olanzapine may also be used to prevent vomiting or nausea caused by chemotherapy, a cancer drug treatment. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.
Schizophrenia can cause symptoms such as hallucinations e. Nonmedicinal ingredients: aspartame, gelatin, mannitol, sodium methyl paraben, and sodium propyl paraben. The usual starting dose of olanzapine tablets for adults with schizophrenia is 5 mg to 10 mg once price of zyvox iv at the same time each day. If the daily dose is increased, it is usually raised not more than once a week, and in increments of 5 mg. The dosage range is 5 mg to 20 mg daily.
It's also used to treat depression when used with other medications. By taking this drug you may be able to decrease hallucinations, reduce feelings of agitation, and think more clearly and positively.
Olanzapine belongs to group of medications known as antipsychotic agents. How should I use this medication?
Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week, since steady state for olanzapine would not be achieved for approximately 1 week in the typical patient. Dosing in Special Populations — The recommended starting dose is 5 mg in patients who are debilitated, who have a predisposition to hypotensive reactions, who otherwise exhibit a combination of factors that may result in slower metabolism of olanzapine e.
Your doctor may be using this medication for another reason. If you are unclear why this medication is being prescribed, please ask your doctor. Olanzapine is usually taken once a day with or without food. Olanzapine should be taken at the same time each day as directed by your doctor. Usually, your doctor will start with a low dose of olanzapine that is best suited to your age and zyprexa olanzapine 5 mg.
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