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The researchers say that the drug has ''disappointingly little overall benefit'' and is not cost-effective, and that better treatments are needed. Even the drugs' staunchest advocates say that they offer modest benefits at best, affording perhaps a short delay in a patient's decline. But when small changes in functioning occur, it may be hard to tell whether they are owing to the drug or to the ups and downs of the disease itself. Although the patients taking the drug did have slightly higher scores on mental tests, after three years they did not differ from the placebo group in their rates of being put in a nursing home or becoming disabled. There were also no significant differences between the groups in behavioral or psychological symptoms or in the emotional well-being of the people taking care of the patients. But the Alzheimer's Association issued a statement saying that the study should ''not dictate individual treatment decisions.
Food and Drug Administration, the first regulatory agency in the world to do so. In, German physician Dr. Finally, when Auguste died in, he got his chance to find out. Later analysis revealed that these were mostly composed of buy aciphex online, a type of protein. These deposits interfere with the action of the neurotransmitter acetylcholine which is involved in memory and cognition. Drugs such as donepezil Aricept, that prevent the breakdown of acetylcholine by the enzyme cholinesterase were approved over two decades ago, and while such cholinesterase inhibitors can result in a small benefit in mental function over the short term, they do not change the progression of the disease.
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Aricept, also known as Donezepil, does not slow down the progression of the disease in the brain, but it can slow down further decline in cognition, usually for around six months. It was approved in November, and was ranked the most effective in a recent study. However, it was also ranked as the drug with the most side effects, like vomiting and nausea. Aricept is also known as Donepezil hydrochloride, Eranz and E Aricept is an oral medication taken once daily that stops the breakdown of acetylcholine, tegretol tab 200mg brain chemical that helps nerve cells communicate with one another. The effects of Aricept are limited.
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