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Common side effects include dizziness, headaches, diarrhea, and back pain. Food and Drug Administration FDA has determined that the benefits of olmesartan continue to outweigh its potential risks when used for the treatment of patients with high blood pressure according to the drug label. For patients with possible depletion of intravascular volume e. Olmesartan may be administered with other antihypertensive agents. Olmesartan may be administered with or without food.
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Benicar HCT includes hydrochlorothiazide, a thiazide diuretic. Benicar and Benicar HCT are both supplied as tablets for oral administration. Patients titrated to the individual components olmesartan and hydrochlorothiazide may instead receive the corresponding dose of Benicar HCT. Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation and renal reabsorption of sodium. Olmesartan blocks the vasoconstrictor effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in vascular smooth muscle. Its action is, therefore, independent of the pathways for angiotensin II synthesis.
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Authored by Dr. Michael Terrance Havig, MD