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Begin days before travel, daily during travel, and for 7 days after leaving. Begin days before travel, daily during travel, and for 4 weeks after leaving. Adults: mg base mg salt, weekly. Begin weeks before travel, weekly during travel, and for 4 weeks after leaving. Choosing a Drug to Prevent Malaria. Recommended drugs for each country are listed in alphabetical order and have comparable efficacy in that country. For all medicines, also consider the possibility of drug-drug interactions with other medicines that the person might be taking as well as other medical contraindications, such as drug allergies. Good for last-minute travelers because the drug is started days before traveling to an area where malaria transmission occurs Some people prefer to take a daily medicine Good choice for shorter trips because you only have to take the medicine for 7 days after traveling rather than 4 weeks Very well tolerated medicine — side effects uncommon Pediatric tablets are available and may be more convenient Cannot be used by women who are pregnant or breastfeeding a child less than 5 kg Cannot be taken by people with severe renal impairment Tends to be more expensive than some of the other options especially for trips of long duration Some people including children would rather not take a medicine every day. In those instances, they may not have to take an additional medicine Can be used in all trimesters of pregnancy Cannot be used in areas with chloroquine or mefloquine resistance May exacerbate psoriasis Some people would rather not take a weekly medication For trips of short duration, some people would rather not take medication for 4 weeks after travel Not a good choice for last-minute travelers because drug needs to be started weeks prior to travel.
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