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Irbesartan is used alone or in combination with other classes of antihypertensive agents in the management of hypertension. Angiotensin II receptor antagonists, such as irbesartan, are considered one of several preferred antihypertensive drugs for the initial management of hypertension; other options include angiotensin-converting enzyme ACE inhibitors, calcium-channel blockers, and thiazide diuretics. While there may be individual differences with respect to specific outcomes, these antihypertensive drug classes all produce comparable effects on overall mortality and cardiovascular, cerebrovascular, and renal outcomes. Efficacy of irbesartan for the management of hypertension has been established by controlled studies of weeks' duration in patients with hypertension of mild to moderate severity in outpatient settings. Like ACE inhibitors, angiotensin II receptor antagonists such as irbesartan may produce a smaller blood pressure response in hypertensive black patients compared with nonblack patients.

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It is unknown if this drug passes into breast milk. These drugs may react with irbesartan and cause avapro generic price effects in the body. Possible drug interactions with Avapro include This will increase your risk of having a stroke or heart attack. There is positive evidence of human fetal risk during pregnancy. Angiotensin II is a chemical naturally found in the body that is responsible for contracting the muscles in blood vessels. Glyburide is used in the treatment of diabetes, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

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