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Hoffmann La Roche Kaiseraugst F. Crestor is a medication used in the management of a variety of lipid disorders, including some conditions that lead to high cholesterol. Crestor, like atorvastatin Lipitor, ezetimibe Zetia, pitavastatin Livalo, pravastatin Pravachol and simvastatin Zocor, belongs to a class of medications known as statins that works as HMG-CoA reductase inhibitors. As this type of medication, Crestor blocks the actions of the enzyme HMG-CoA reductase, the rate-controlling step in a metabolic process that produces mevalonic acid and leads to the synthesis of cholesterol.

Because of this, Crestor medication is indicated for use in people with hyperlipidemia, hypertriglyceridemia, and other types of lipid disorders. After oral administration, Crestor is not actively metabolized by the body and the majority of the drug is found bound to proteins in the plasma. Plasma levels tend to peak within 5 hours after oral administration of Crestor medication.

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