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Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. Cautions Taking estrogen by itself without concurrent progesterone therapy may increase the risk of endometrial cancer. Estrogen therapy may increase the risk of dementia in postmenopausal women. Estrogen plus progesterone hormone-replacement therapy may increase the risk of breast cancer. Philadelphia, PA: Pfizer;

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Wyeth, LLC was an American pharmaceutical company. Its headquarters moved to Collegeville, Pennsylvania, and Madison, New Jersey, before its headquarters were consolidated with Pfizer 's in New York City after the merger. In, on the suggestion of doctors, they began to manufacture large quantities of commonly ordered medicines. They were successful, and in they began supplying medicines and beef extract to the Union army during the Civil War. In, Henry Bowers, an employee of Wyeth, developed one of the first rotary compressed tablet machines in the United States. This enabled the mass production of medicines with unprecedented precision and speed. It was successful, and the Wyeth brothers won multiple awards at the Centennial Exhibition. In, Wyeth opened its first international facility in Montreal, Canada, and began vaccine production.

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