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Exacerbation of angina and, in some cases, myocardial infarction occurrence after abrupt discontinuance. When discontinuing long-term administration of beta blockers particularly with ischemic heart disease, gradually reduce dose over weeks and carefully monitor. If angina markedly worsens or acute coronary insufficiency develops, reinstate beta-blocker administration promptly, at least temporarily in addition to other measures appropriate for unstable angina. Warn patients against interruption or discontinuance of beta-blocker therapy without physician advice. Because coronary artery disease is common and may be unrecognized, slowly discontinue beta-blocker therapy, even in patients treated only for hypertension. Long-term beta blocker therapy should not be routinely discontinued before major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures. Avoid beta-blockers without alpha1-adrenergic receptor blocking activity in patients with prinzmetal variant angina; unopposed alpha-1 adrenergic receptors may worsen anginal symptoms.

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It is used to treat hypertension high blood pressure, angina chest pain and arrhythmia irregular heart rhythm. Therefore, it can also be used to prevent heart attacks and migraine headaches. It also controls shakiness of the body by blocking abnormal nerve signals between the brain and the muscles. It is also not suitable for use in patients with heart block, history of heart attack or heart failure. Consult your doctor if any of these side effect troubles you. It works by blocking the actions of certain chemical messengers such as adrenaline and noradrenaline in our body that controls the function of the heart, brain and kidneys and lungs.

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