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Cognitive enhancing drugs are claimed to improve cognitive functions such as learning and attention.
Modafinil, sold under the brand name Provigil among others, is a central nervous system CNS stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer to improve wakefulness, in animal and human studies the research on its effectiveness for this use is not conclusive.
The Agency's Committee for Medicinal Products for Human Use CHMP has concluded that the benefits of modafinil-containing medicines continue to outweigh their risks but that their use should be restricted to the treatment of narcolepsy. Once the PhVWP had received and started its assessment of the data, the working party had further concerns about the medicines, and consequently, on 14 May, the UK medicines regulatory agency asked the CHMP to carry out a full assessment of the benefit-risk balance of modafinil-containing medicines, and to issue an opinion on whether their marketing authorisations should be maintained, varied, suspended or withdrawn across the European Union.
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However, the final decision will always be the prescriber's. This condition causes people to spontaneously fall asleep. It is also used to treat other sleeping disorders such as those experienced by shift workers or those suffering from sleep apnea. It can also be prescribed to treat ADHD. While there are uses of modafinil which are purported to help people stay alert and awake, this drug may not be marketed as a nootropic in the UK. It may only be used as prescribed as a treatment for narcolepsy or other conditions listed above.
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Modafinil is becoming increasingly popular in Europe. In recent years, however, the drug has become increasingly popular as a cognitive enhancer, with people using it to help improve their focus, concentration, and memory.
Although the exact mechanism of operation is unclear, it is thought to work by altering the concentration of natural chemicals neurotransmitters in the brain. Modafinil belongs to a larger group of substances known as nootropics.
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