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Zand struggles with the side effects of taking modafinil. It was a normal Tuesday morning when my friend first told me about smart drugs. They're just pills that make you concentrate, she explained. She was taking them to deal with her big day ahead. But they are also being taken, in growing numbers, by people looking to work more effectively. Modafinil was dubbed the world's first safe smart drug by researchers at Harvard and Oxford universities who suggested its effects were low risk when taken in the short term.
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And the results have been surprising to say the least. It literally blew my mind — in a good way. More about my experience with the smart drug a little later. First, let me cover some basics. Nootropics are gaining popularity among professional gamers, college-goers and top company executives in the west. It promotes wakefulness and is usually prescribed to patients who have narcolepsy, a long-term neurological disorder that decreases the ability to regulate sleep-wake cycles.
Modafinil is an analeptic drug, prescribed for narcolepsy, obstructive sleep apnea and shift work disorder. Headache, nervousness, insomnia, agitation, confusion, personality disorders, tremor, anxiety; GI disturbances; hypertension, palpitations, tachycardia; angioedema; psychosis, depression, mania, abnormal LFTs. May increase metabolism of ciclosporin, oral contraceptives. Uncontrolled moderate to severe hypertension or cardiac arrhythmias; history of left ventricular hypertrophy or ischaemic ECG changes, chest pain, any clinical signs of mitral valve prolapse. The mechanism of modafinil is unknown but it appears to exert its stimulant effects by reducing GABA-mediated neurotransmission.
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