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A year-old woman received treatment for severe degenerative disease of the lumbar spine with 40 mg of OxyContin twice daily for more than a year. Although she continued to complain of pain and paravertebral muscle spasm, her physician was reluctant to increase the dosage of OxyContin. After taking this regimen for a week without relief, she increased the dosage to eight to 10 tablets a day, assuming this would be safe. A count of her remaining supply of medications verified that she had not taken any extra OxyContin and a drug screen was negative except for opiates. The most likely explanation for this patient's adverse reaction would be a response to the additive depressant effects on the central nervous system CNS of both OxyContin and carisoprodol. Although OxyContin's effects are well known in the medical community, many physicians are unaware that carisoprodol is metabolized to meprobamate Miltown, a Class IV controlled substance with significant physiologic effects and the potential for abuse and dependency. Carisoprodol and OxyContin should only be prescribed concomitantly with extreme caution because of the abuse potential of each drug and because of the potentially dangerous additive CNS-depressant effect of the two drugs.

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Common side effects include headache, dizziness, and sleepiness. Carisoprodol is meant to be used along with rest, physical therapy and other measure to relax muscles after strains, sprains and muscle injuries. Carisoprodol has a unique mechanism of action, qualitatively different from that of meprobamate Miltown. Another danger of misuse of carisoprodol and opiates is the potential to aspirate while unconscious. Carisoprodol is metabolized by the liver and excreted by the kidneys so this drug must be used with caution with patients that have impaired hepatic or renal function.

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A year-old woman received treatment for severe degenerative disease of the lumbar spine with 40 mg of Oxycontin twice daily for over a year. Although she continued to complain of pain and paravertebral muscle spasm, her physician was reluctant to increase the dosage of Oxycontin. One tablet mg of carisoprodol four times daily was prescribed. After taking this regimen for a week without relief she increased the dosage to eight to 10 tablets a day, assuming this would be safe. She was responsive only to painful stimuli.

Carisoprodol is a precursor of meprobamate, an oral anxiolytic with similarities to benzodiazepines. Major adverse somata tabs 350mg are sedation and drowsiness. Because of an increased risk of abuse and addiction 1, 2 carisoprodol was withdrawn from many countries in Carisoprodol dosing should not exceed four doses in a hour period Table Similar to other muscle relaxants, carisoprodol has additive sedative effects when taken with alcohol or other central nervous system CNS depressants. Carisoprodol is converted in the liver to meprobamate Miltown, an intravenous IV controlled substance.

WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Carisoprodol is a central nervous system agent that is FDA approved for the soma tabs 350mg of discomfort associated with acute, painful musculoskeletal conditions in adults. Common adverse reactions include dizziness, somnolence, headache. Contraindications Carisoprodol Tablets are contraindicated in patients with a history of acute intermittent porphyria or a hypersensitivity reaction to a carbamate such as meprobamate. Since the sedative effects of carisoprodol and other CNS depressants e.