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The incubation period was estimated at between 5 to 7 days, but could last as long as 14 days. By 27 April, over 3 million people around the world have been diagnosed with COVID, and more, have succumbed to the disease. As a proportion of patients manifest mild or no symptoms, these numbers are likely an underestimate of the actual number of patients with COVID More disconcertingly, patients are known to shed viruses despite mild or no symptoms, making it essential that a collective approach against COVID incorporate active pharmacological treatment to prevent or mitigate virus pathogenesis prior to its potential evolution to cause respiratory distress. To date, clinical trials have focused on the treatment of hospitalised patients diagnosed with COVID; only few have examined the clinical benefits of pharmacological agents despite few compelling in vitro data.
Fuelled by anti-vaccine and pandemic conspiracy theories online, there has been a surge in demand for the drug from Brazil to South Africa to Lebanon. But manufacturer Merck has said there was no scientific basis for a potential therapeutic effect against Covid and warned of possible safety issues if the drug is administered inappropriately. That has not stopped Indonesian tycoon and government minister Erick Thohir from praising ivermectin and urging domestic production to fight the current outbreak. Efforts to tackle the virus worldwide have been marred by conspiracy theories, often propagated by political leaders and other public figures. In the Philippines, President Rodrigo Duterte has pressured regulators to approve the drug as a Covid treatment. After demand for the drug surged in Latin America, the WHO said in March that any use of the drug as a coronavirus treatment should be limited to clinical trials. Merck has said there is no scientific basis for a potential therapeutic effect from ivermectin against Covid. But manufacturer Merck has said there was no scientific basis for a potential therapeutic effect against COVID and warned of possible safety issues if the drug is administered inappropriately.
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