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Composition - Ivermectin is a mixture of two types of avermectins In the mids, it was found that Streptomyces avermitilis a type of bacteria treated mice infested with Nematospiroides dubius intestinal roundworm attacking rodents. Isolation of Streptomyces avermitilis led to the discovery of ivermectin. Since then, ivermectin for humans has been used to treat roundworms and other parasitic nematodes. Ivermectin tablets for humans, a well-known medicine, is widely used as an antiparasitic drug by the World Health Organization WHO in low- and middle-income countries to treat worm infections, scabies and lice. Ivermectin ivermectin 12mg tablets for humans are rapidly absorbed, reaching maximum plasma concentrations with a broad tissue distribution about 4 hours after a mg dose. After a single standard dose, microfilariae in the skin diminish rapidly within 2—3 days, remain low for months, and then gradually increase; microfilariae in the anterior chamber of the eye decrease slowly over months, eventually clear, and then gradually return. With repeated doses of ivermectin, the drug appears to have a low-level macrofilaricidalaction and to reduce microfilarial production permanently. It is also used as an alternative drug for several other helminthic infections, such as
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