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The discovery of Mectizan has engendered a safe onchocerciasis chemoprevention tool. The number of yearly approved treatment doses has increased rapidly since from, to more than 80 million in and
The disease is endemic in three quarters of the country and there is considerable onchocercal blindness in the north-west. The low population density and extreme poverty the CAR being one of the 20 poorest countries in the world combine to make mass treatment with Mectizan ivermectin, MSD a challenge.
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