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Get the lowest prices on generic medications. We work with your doctor or local pharmacist to take care of transfers, refill requests, and more. This medication is used to help relieve moderate to moderately severe pain. Tramadol is similar to opioid narcotic analgesics. It works in the brain to change how your body feels and responds to pain.
Tramadol has been present on the European market since and was approved for use in the United States in the middle s. Within the years of its use, Tramadol has proven its effectiveness in dealing with pain. There is a range of studies and clinical research that prove that preparation is more effective for pain relief compared to a placebo. This preparation is an opioid, which acts in two ways. Second is weak inhibition of norepinephrine and serotonin reuptake.
Both actions are aimed to produce an analgesic effect and relieve pain. The primary indication for Tramadol intake is the management of moderate and moderately-severe pain. The drug can be effectively used in patients suffering from acute pain in the post-surgery period and chronic pain associated with osteoarthritis. However, such things cannot be referred to every patient getting treatment with this drug. Here are the basics that will help you go through the therapy with Tramadol with minimum-to-no negative consequences Due to a range of medical reasons, you may be not recommended to take Tramadol to soothe the pain.
Opioid analgesics are not recommended to children under the age of 16 due to a lack of evidence of its safety in this group of patients. Despite the drug label claims pregnant individuals can use Tramadol when the expected benefits for the mother prevail over the possible risks for the fetus, the post-marketing experience of using Tramadol in gestation revealed a range of negative consequences for such patients. Lactating individuals should stop breastfeeding their babies if they initiate treatment with this preparation.
While Tramadol is generally considered one of the safest representatives of opioid analgesics, this preparation still has a range of side effects that may appear in the course of treatment. The incidence and severity of listed reactions progress with the extension of the term of treatment and the dose increase. The incidence of this severe adverse reaction is unknown.
Even one pill of Tramadol can trigger serotonin syndrome, which is characterized by restlessness, confusion, delusion, muscle rigidity, insomnia, and some other reactions. If left without medical attention, this condition may exacerbate and become life-threatening. Therefore, timely medical assistance is essential for such patients. Like other opioid medications, Tramadol gets into interaction with many other preparations.
This may provoke the growing risks for severe adverse effects, overdose, or a lack of efficacy of treatment.
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Pain management is an important aspect of medical care to enhance the quality of life for individuals with chronic or acute pain. One of the commonly prescribed pain relievers is Tramadol, an opioid medication used to relieve moderate to severe pain. Tramadol has been widely adopted for its effectiveness in managing different types of pain, including postoperative pain, cancer pain, and chronic pain. Pain is a common experience that everyone goes through at some point in their life.
As is typical of opioids, common side effects include constipation, itchiness, and nausea. Tramadol is used primarily to treat mild to severe pain, both acute and chronic. People with specific variants of CYP2D6 enzymes may not produce adequate amounts of the active metabolite desmetramadol for effective pain control. Tramadol may not provide adequate pain control for individuals with certain genetic variants of CYP2D6 enzymes as they metabolize tramadol to the active molecule.
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Authored by Dr. Linda Suriyakham, PHD