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The is a dose of enzodiazepine that is administered using a soluble film that is placed inside the cheek. It is intended for treatment of acute uncontrolled seizures in selected, refractory patients with epilepsy on stable regimens of AEDs who need intermittent diazepam to control increased seizure activity. The current standard of care rescue therapy for this indication is Diastat diazepam rectal gel. With the commercial foundation we have built for Sympazan, we will be prepared to launch Libervant quickly, if approved by the FDA for U. The trial demonstrated that Libervant offered similar systemic diazepam exposures to the reference drug and with significantly less variability.
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Common side effects include sleepiness and trouble with coordination. Adverse effects of benzodiazepines such as diazepam include anterograde amnesia, confusion especially pronounced in higher doses and sedation. The elderly are more prone to adverse effects of diazepam, such as confusion, amnesia, ataxia, and hangover effects, as well as falls. Long-term use of benzodiazepines such as diazepam is associated with drug tolerance, benzodiazepine dependence, and benzodiazepine withdrawal syndrome. Tolerance to the cognitively impairing fake valium 10mg of benzodiazepines does not tend to develop with long-term use, and the elderly are more sensitive to them.
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Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. Common side effects include sleepiness and trouble with coordination. Diazepam was patented in by Hoffmann-La Roche. Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures e.
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