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IV: Titrate dose to 10 mg or less immediately before procedure, not to exceed cumulative dose of 20 mg; reduce dose of narcotic by one third or omit, OR. Renal impairment: No dose adjustment recommended unless administered for prolonged period; decrease dose in prolonged periods. Orphan designations for management of acute repetitive seizures or for Dravet syndrome by various administrative routes eg, intranasal, buccal soluble film, or SC. Potentially toxic dose in patients 0. Due to long-acting metabolite, not considered a drug of choice in the elderly; associated with falls.

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Diazepam is an anxiolytic, anticonvulsant and central muscle-relaxant. Diazepam is used to relieve anxiety and provide sedation in severe acute anxiety or agitation and for the management of agitation associated with delirium tremens. Acute convulsions including status epilepticus, also convulsions due to poisoning and febrile convulsions. As an adjunct during endoscopy, in dentistry, surgery, radiology. Initially an IV dose of 0. The usual adult dose is 10 — 20 mg but higher doses may be necessary according to the clinical response.

This is a high-risk preparation. Calculate valium 2 mg injectable required quantity of each ingredient for the total amount to be prepared. Accurately weigh or measure each ingredient. Mix the propylene glycol, alcohol, and benzyl alcohol. Dissolve the diazepam and benzoic acid in the solution.

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Diazepam Injection, USP is a sterile, nonpyrogenic solution intended for intramuscular or intravenous administration. Note: Solution may appear colorless to light yellow. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, valium 2 mg injectable induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs.

Doctors prescribe diazepam to suppress symptoms caused by anxiety, agitation, and psychic tension. It can also be useful for relief of acute agitation, tremors and hallucinations if you have an alcohol withdrawal syndrome. Can also be used to combat diseases caused by spasticity due to disorders from both spinal as supraspinal origin, such as cerebral palsy and paraplegia as well as athetosis and generalized stiffness syndrome. Diazepam may be used as adjuvant treatment of seizure disorders. Diazepam is indicated for the treatment of febrile seizures in children over 1 year about 10 kg and epileptic seizures ; in states of anxiety, tension, and anguish or as a sedative in minor surgery and diagnostic or endoscopic procedures.

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Unlabeled use s: Treatment of irritable bowel syndrome; relief of panic attack. Individualize dosage; increase cautiously. In acute conditions injection may be repeated within 1 hr, but q 3 to 4 hr is usually satisfactory. Dosage and route vary with indication and age. Larger doses may be necessary in tetanus.

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USES: Diazepam is used to treat anxiety and muscle spasms. It is also used in patients with alcohol withdrawal to prevent seizures and treat other symptoms e. This medication is also used for short-term treatment of serious seizures that do not stop status epilepticus. It is not for ongoing daily use to prevent seizures. It is also used before surgeries or procedures to cause drowsiness, decrease anxiety, and cause forgetfulness about the procedure or surgery. It works by enhancing the effects of a certain natural chemical in the body GABA that causes calm.

These datasets underpin the analysis presented in the agency's work. Explore our wide range of publications, videos and infographics on the drugs problem and how Europe is responding to it. Benzodiazepines are widely used in medicine to treat anxiety and insomnia. They act as depressants of the central nervous system CNS. Chlordiazepoxide Librium was valium 2 mg injectable first to be synthesised in and introduced into medicine in