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Inhaled short-acting beta-2 agonist SABA ; available in nebulizer solutions and inhalers Used in adults and pediatrics for the management of asthma, acute bronchospasm, and prevention of exercise-induced bronchospasm Used in treatment of COPD in adults. In some patients, 90 mcg 1 puff every 4 hours may be sufficient. For the acute treatment of severe episodes, the National Asthma Education and Prevention Program Expert Panel recommends 4 to 8 puffs every 20 minutes for up to 4 hours, then 4 to 8 puffs every 1 to 4 hours as needed.
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Nebulizer inhalation solution: Do not administer in the same infusion with other medications. Uses Relief of severe bronchospasm associated with acute exacerbations of chronic bronchitis and bronchial asthma, and acute attack of bronchospasm -Treatment of status asthmaticus. Inhalation powder: 2 inhalations mcg orally 15 to 30 minutes before exercise Inhalation capsule: 1 inhalation mcg 15 minutes before exercise Uses: Prevention of exercise-induced bronchospasm.
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The usual effective dose is 4mg three or four times per day. If adequate bronchodilation is not obtained each single dose may be gradually increased to as much as 8mg. However, it has been established that some patients obtain adequate relief with 2mg three or four times daily. In elderly patients or in those known to be unusually sensitive to beta-adrenergic stimulant drugs, it is advisable to initiate treatment with 2mg three or four times per day. The product is not recommended for children under 2 years of age.
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Oral albuterol overdose with electrocardiographic changes and cardiac ischemia. A year-old girl buy albuterol 8mg a history of depression was brought to the emergency department ED by emergency medical services EMS for nausea and vomiting. Five hours prior to presentation, she had intentionally taken 30 8-mg albuterol sulfate tablets that had been prescribed to her mother more than 10 years previously. She was transferred to a tertiary care facility.
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Administration of undiluted salbutamol injection through a central venous catheter is not licensed. See Respiratory system, inhaled drug delivery. Healthcare professionals are advised that home use of nebulisers for the acute treatment of asthma in children and adolescents should only be initiated and managed by asthma specialists. Home use of nebulisers for this purpose, without adequate medical supervision, can mask a deterioration in the underlying disease, which could result in delays in seeking medical attention and be fatal or have serious consequences.
Authored by Dr. Scott Shapiro, MD