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This development was credited largely due to the introduction of generic products. Sildenafil is available as a generic drug in the United States, labeled for pulmonary arterial hypertension. In the United States, Pfizer received two patents for sildenafil: one for its indication to treat cardiovascular disease marketed as Revatio and another for its indication to treat erectile dysfunction marketed as Viagra.

 

The substance is the same under both trade names. In, Pfizer filed a patent covering the substance sildenafil and its use to treat cardiovascular diseases. The patent on Revatio indicated for pulmonary arterial hypertension rather than erectile dysfunction expired in late In, Pfizer filed a patent covering the use of sildenafil to treat erectile dysfunction. Teva sued to have the latter patent invalidated, but Pfizer prevailed in an August federal district court case. Drug for erectile dysfunction and hypertension.

 

For other uses, see Viagra disambiguation. D Y citrate: D Y. British Journal of Clinical Pharmacology. Annals of the Rheumatic Diseases. PDE-5 inhibitors appear to have significant but moderate efficacy in secondary Raynaud's phenomenon. International Journal of Urology. Retrieved 15 February Retrieved 24 November Phosphodiesterase inhibitors e. Commonly-used classes of drugs. Archived from the original on 10 June Food and Drug Administration. Archived from the original on 22 October The American Journal of Cardiology.

 

Use of sildenafil Viagra in patients with cardiovascular disease. Journal of the American College of Cardiology. Journal of the American Pharmacists Association. International Journal of Impotence Research. The Journal of Family Practice. Archived from the original on 26 January Retrieved 10 February Archived from the original on 14 August Archived from the original on 5 March Retrieved 28 November Journal of Pharmaceutical and Biomedical Analysis. Journal of Toxicology and Environmental Health.

 

Forensic Science International. Archived from the original on 4 March Archived from the original on 18 January The New England Journal of Medicine. The Pharmaceutical Journal.

 

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