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Treatment of paediatric patients aged 1 year to 17 years old with pulmonary arterial hypertension. Treatment should only be initiated and monitored by a physician experienced in the treatment of pulmonary arterial hypertension. In case of clinical deterioration in spite of Revatio treatment, alternative therapies should be considered. The recommended dose is 20 mg three times a day TID. Physicians should advise patients who forget to take Revatio to take a dose as soon as possible and then continue with the normal dose. Patients should not take a double dose to compensate for the missed dose. Higher than recommended doses should not be used in paediatric patients with PAH see also sections 4.

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Sildenafil is a medicine used to treat erectile dysfunction. It increases blood flow to the penis to help men get an erection. At least two-thirds of men have improved erections after taking it. Sildenafil is also sometimes used to treat pulmonary hypertension high blood pressure in the blood vessels that supply the lungs. It comes as tablets that you swallow, chewable tablets, and as a liquid that you drink.

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Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared. Accurately weigh or measure each ingredient. Obtain the required number of sildenafil citrate tablets or the required quantity of powder and place in a mortar. Pulverize the tablets, if used, to a fine powder. Add a small quantity of the Ora-Plus:Ora-Sweet mixture and mix to a smooth paste.

It is only for research purposes and not for human consumption. It causes vasodilation in the penis of animal test subjects and blocks the breakdown of cyclic guanosine monophosphate cGMP is produced in the penis during sexual stimulation. In the lungs, it may also decrease the systolic and diastolic blood pressure mildly. These two main actions could result in the improvement of Erectile Dysfunction and Pulmonary Arterial Hypertension. Also, sildenafil may improve cognitive function in animals with hepatic encephalopathy. It exhibits anti-amnesic activity against intracerebroventricular streptozotocin-induced memory loss and vascular dementia in the experimental animals.