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Olmesartan is an angiotensin receptor blocker ARB used in the treatment of hypertension. Olmesartan belongs to the angiotensin II receptor blocker ARB family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 AT1 and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Olmesartan also affects the renin-angiotensin aldosterone system RAAS, which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. The angiotensin II receptor blocker ARB family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.

 

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In addition to the use of this medicine, treatment for your high blood pressure may include weight control and rotes viagra 130 mg in the types of foods you eat, especially foods high in sodium salt. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal.

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