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Nevertheless, the examples used in this book amount to over are listed for easy reference in Appendix I. If a drug is to have a therapeutic effect on the body, it first has to reach its site of action. In order to do this a drug has to be administered in some way. Unless the route of administration is directly into the blood stream, the drug has to be absorbed, usually by diffusion.

It may irritate sensitive areas. It is prepared as Whitfields ointment and available as a pharmacy medicine. This group of drugs is effective against many fungi. Imidazoles are often the drugs of first choice for treating tinea because they are more effective than other topical drugs described above.

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A small percentage of patients do not respond to the drug. These individuals are insensitive or unresponsive to the drug. An equally small percentage responds in an exaggerated manner.

British Hypertension Society guidelines for the management of hypertension have recently been changed to be in line with European guidelines. Drugs that are used to treat hypertension include diuretics, ACE inhibitors, angiotensin II receptor antagonists, β-blockers, calcium channel blockers, α acting antihypertensives. Groups of drugs are described together with their relevant therapeutic indications because often the same drugs are used for different conditions. Cardiac glycosides are used to treat cardiac failure and atrial flutter and atrial fibrillation. Digoxin and digitoxin are cardiac glycosides that improve cardiac contractility, which in turn increases cardiac output.

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