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PTH, together with vitamin D, raises plasma calcium levels by increasing activity of osteoclasts, which results in release of calcium from bone; by increasing reabsorption of calcium by the kidney and by increasing absorption of calcium from the intestine. Deficiency of PTH is treated with injections of calcium and calcitriol (a vitamin D analogue). High levels of calcium in blood plasma cause the release of calcitonin from the thyroid gland, which inhibits the reabsorption of calcium from bone by inhibiting osteoclasts. Calcitonin is used in the treatment of Pagets disease and osteoporosis. The adrenal glands are situated one above each kidney.
Authored by Dr. Javier P Berrios, MD