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Sildenafil citrate, the key ingredient of this drug, treats the irregular functioning of men reproductive system by increasing the blood flow to the man reproduction organ. It boosts the love-making stamina in the impotent men by allowing them to obtain hard erection during the sexual stimulation. The importance of this medicine is that it cures the erection problems irrespective of its cause and age of the man. It is the well known impotence pill that stops the occurrence of the erectile dysfunction by providing the sufficient amount of blood needed for hard erection of reproductive system. Penegra is the most used for treating men impotence issue.

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Sildenafil is used in the treatment of Erectile Dysfunction. Headache, flushing, respiratory tract infection, angina pectoris, AV block, migraine, syncope, tachycardia, postural hypotension, MI, cerebral thrombosis, cardiac arrest, paraesthesia, tremor, depression, herpes simplex, skin ulcer, oesophagitis, abnormal LFT, rectal haemorrhage, hypoglycaemic reaction, arthritis, deafness, retinal vascular disease, photosensitivity, accidental fall. Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Plasma concentrations are increased by ritonavir.

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Most men, at some point of time in their lives come across a nasty problem where they are not able to get or maintain their erections even during sexual intercourse. Viagra is one of the blockbuster molecules used for the treatment of ED. Penegra, like the brand equivalent Viagra, contains the penegra cheap ingredient Sildenafil Citrate. Sildenafil citrate is the archetype PDE-5 inhibitor which are class of medications designed for the treatment of ED. When this happens, Nitric Oxide levels in the body increase which further improves the production of cGMP in the body. All this lead to dilation of the arteries and the relaxation of muscles at the penile region.

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