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Nutrition and M etabolism in Acute Renal Failure O ne Use of solutions of EAA alone is based on principles established for should be aware of the fact that the am ino acid analogue N -acetyl treating chronic renal failure CRF with a low-protein diet and an tyrosine, which previously was used frequently as a tyrosine EAA supplement. This may be inappropriate as the metabolic adapta- source, cannot be converted into tyrosine in hum ans and m ight tions to low-protein diets in response to CRF may not have occurred even stim ulate protein catabolism. Plus, there are fundamental differences in the Despite considerable investigation, there is no persuasive evi- goals of nutritional therapy in the two groups of patients, and conse- dence that am ino acid solutions enriched in branched-chain am ino quently, infusion solutions of EAA may be sub-optimal. System atic Thus, a solution should be chosen that includes both essential studies using glutam ine supplem entation for patients with ARF are and nonessential am ino acids EAA, N EAA in standard propor- lacking see Fig.