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Only about potential interactions clinically manifest themselves. Factors that determine those individuals who will show symptoms of drug interaction are unknown. The principal groups of drugs that are most likely to cause drugdrug interactions are anticoagulants, buy xanax cheap online hypoglycaemics, monoamine oxidase inhibitors (for depression), cytotoxics.

Metoclopramide is also an antiemetic, which can be useful in radiological examinations and to counteract the effects of therapeutic radiography. The antiemetic effect is due to the blocking of dopamine receptors in the chemotrigger zone of the medulla. The chemotrigger zone is sensitive to potentially harmful chemicals in blood. Adverse effects of metoclopramide include rashes and pruritis. In high dose, injection of metoclopramide can cause sedation and facial muscle spasms due to effects on dopamine receptors in the brain.

What do you think might have happened to Ms. Clarke after the previous operation. How can you reassure her that this will not happen again. You should be able to answer these review questions from the material in this chapter. injection of drugs.

Drugs may also affect the foetus at later stages of pregnancy so the best advice is to avoid drug use during pregnancy unless absolutely necessary. In cases of chronic maternal disease, the risks of stopping drug therapy have to be balanced against the benefits to the developing foetus. For example, it would be dangerous to cease treatment for chronic conditions such as asthma or epilepsy. In these situations, drugs least likely to harm the foetus should be used. Usually drug therapy does not interfere with breast feeding but it is possible for effective amounts of drug to pass into the milk, particularly if the drug behaves as a weak base.

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