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Objective: To assess the cost-effectiveness of orlistat plus a calorie-controlled diet compared with a calorie-controlled diet alone for the treatment of overweight and obese patients in Ireland. The model incorporated known relationships between weight loss and quality of life utility gain, and weight loss and reduction in risk of type 2 diabetes T2DM to predict the impact of weight loss on quality-adjusted-life-years QALYs gained and on the onset of T2DM. The costs associated with each treatment arm included the acquisition cost of orlistat, cost of a calorie-controlled dietary programme and monitoring and treatment costs associated with T2DM.
Orlistat is part of a group of medicines known as lipase inhibitors which work in the intestines to prevent the absorption of some of the consumed in your diet. This fat is then eliminated by passing it through your faeces. Xenical Orlistat Weight Loss Tablets.
Weight loss treatment is most effective when used consistently, alongside important lifestyle changes. Each pre-filled pen contains 4 doses. You stay on each dose for at least 4 weeks.
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Authored by Dr. Michael J Thomas, MD