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Pain or discomfort in the chest, throat, jaw, or arms caused by severe, but temporary, lack of blood and oxygen to a segment of the heart muscle defines angina pectoris. Atherosclerosis atheroma of the coronary arteries causes obstruction of blood flow and deprives the heart muscle of blood. Obstructive atheromatous CAD leads to stable or unstable angina, fatal or nonfatal myocardial infarction MI, sudden death, heart failure, arrhythmias, atrial fibrillation, and thromboembolism that may cause stroke. Encyclopedia of Heart Diseases Edition. Boydak B, Nalbantgil S, Fici F et al A randomised comparison of the effects of nebivolol and atenolol with and without chlorthalidone on the sexual function of hypertensive men. Celik T, Iyisoy A, Kardesoglu E et al The anti-inflammatory effects of nebivolol in human coronary smooth muscle cells: clinical implications. Int J Cardiol — Google Scholar.
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Bactericidal activity of azithromycin is stronger by binding to the ribosomes of harmful bacteria and inhibiting protein synthesis. Gram-negative bacteria: Haemophilus influenzae, parainfluenzae and ducreyi, Moraxella catarrhalis, Acinetobacter, Yersinia, Legionella pneumophilia, Bordetella pertussis and parapertussis; Neisseria gonorrhoeae and Campylobacter sp. Besides, azithromycin is also active against Listeria monocytogenes, Mycobacterium avium, Mycoplasma pneumoniae and hominis, Ureaplasma urealyticum, Toxoplasma gondii, Chlamydia trachomatis and Chlamydia pneumoniae, Treponema pallidum and Borrelia burgdorferi. Peak plasma concentrations are achieved 2 to 3 hours after oral administration. Azithromycin is mainly distributed to tissues, such as lungs, tonsil, prostate, granulocytes, macrophages. A small amount of azithromycin is demethylated in the liver, and it is excreted in bile as unchanged drug and metabolites. Azithromycin is used to treat uncomplicated genital infections due to Chlamydia trachomatis or non-multiresistant Neisseria gonorrhoeae.
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Drug Emycin have composition Erythromycin, treatment of respiratory tract infections, gastrointestinal tract infections, skin and soft tissue infections, neonatal conjutctivitis and Chlamydial conjunctivitis. Emycin DHG contains erythromycin that is a macrolide antibiotic with a wide spectrum of activity. Erythromycin and other macrolides bind reversibly to the 50S subunit of the ribosome, inhibit the zithromax 250mg price synthesis. The actions of erythromycin are increased at moderately alkaline pH up to about 8. Erythromycin has a broad spectrum of activity, including Gram-positive cocci, Streptococcus pneumoniae, Streptococcus pyogenes. Staphylococcus aureus, Bacillus anthracis, Corynebacterium diphteria, Erysipelothris rhusioparthiae, Listeria monocyogenes, Anaerobic Clostridium spp.
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Pharmacological action Pharmacokinetics Why is azithromycin prescribed? What are the side effects you encounter while taking this medicine?
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Pharmacological action Pharmacokinetics Why is azithromycin prescribed? It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. Pharmacokinetics azithromycin rapidly absorbed from the gastrointestinal tract. Ingestion reduces the absorption of azithromycin. C max in plasma is reached after hours. This medicine rapidly distributed in tissues and biological fluids.
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