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Pliva put its azithromycin on the market in Central and Eastern Europe under the brand name Sumamed in Pfizer launched azithromycin under Pliva's license in other markets under the brand name Zithromax in Azithromycin is available as a generic medication. During active phagocytosis, large concentrations are released. Azithromycin prevents bacteria from growing by interfering with their protein synthesis. Azithromycin was discovered in by the Croatian pharmaceutical company Pliva and approved for medical use under the brand name Sumamed in Azithromycin has relatively broad but shallow antibacterial activity.

 

Azithromycin is commonly administered in film-coated tablet, capsule, oral suspension, intravenous injection, granules for suspension in sachet, and ophthalmic solution. Clindamycin Lincomycin Pirlimycin. The concentration of azithromycin in the tissues can be over 50 times higher than in plasma due to ion trapping and its high lipid solubility. Common side effects include nausea, vomiting, diarrhea and upset stomach. Scholia has a profile for azithromycin Q Chloramphenicol Azidamfenicol Thiamphenicol Florfenicol.

 

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No harm has been found with use during pregnancy. Not to be confused with Erythromycin. It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. Zithromax, Azithrocin, Sumamed, others 1. World Health Organization model list of essential medicines: 21st list Geneva: World Health Organization. By mouth capsule, tablet or suspension, intravenous, eye drop.

 

Disposition of Toxic Drugs and Chemicals in Man 8th ed. The safety of the medication during breastfeeding is unclear. Oxford: Oxford University Press. Occasionally, people have developed cholestatic hepatitis or delirium. Neisseria gonorrhoeae is normally susceptible to azithromycin, 22 but the drug is not widely used as monotherapy due to a low barrier to resistance development. Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids.

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