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Acyclovir belongs to the family of medications known as antivirals. It is also used for the acute treatment of herpes zoster shingles and varicella chickenpox. All these infections are caused by viruses. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis 10, 11, 12, 13, 14, Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Acyclovir is a nucleoside analog that inhibits the action of viral DNA polymerase and DNA replication of different herpesvirus. Acyclovir is becomes acyclovir monophosphate due to the action of viral thymidine kinase. Comprehensive structured data on known drug adverse effects with statistical prevalence. Structured data covering drug contraindications.
Manufacturer: GlaxoSmithKline. Distributor: Zuellig Pharma. Dispersible tab: Dispersible Tablets containing zovirax 800mg oral mg or mg aciclovir. Oral susp: Oral suspensions containing mg aciclovir per 5 ml. Powd for inj: Sodium hydroxide; Nitrogen; Water for injection. Pharmacotherapeutic group: Direct acting antivirals, Nucleosides and nucleotides excl.
The Food and Drug Administration FDA approved acyclovir to treat viral infections from the varicella virus that causes chicken pox and shingles, as well as infections from the virus that causes genital herpes. Sometimes doctors prescribe acyclovir to treat herpes infections in people with HIV. The drug works by preventing viruses from dividing and multiplying. The FDA approved acyclovir in the s. Acyclovir is one of the oldest drugs used to treat herpes simplex viruses and remains the first line of treatment for these infections.
Physicochemical properties: Acyclovir is a white, crystalline powder with a maximum solubility in water of 1. Those most likely to benefit are patients who experience severe, prolonged recurrences; such intermittent therapy may be more appropriate than suppressive therapy when these recurrences are infrequent. Treatment of Initial Infection of Herpes Genitalis: mg one mg tablet or one teaspoonful of suspension every 4 hours, 5 times zovirax 800mg oral for a total of 1 g daily for 10 days. The initial recommended dose is mg one mg tablet or one teaspoonful of suspension three times daily. This can be increased if breakthrough occurs up to a dosage of one mg tablet or one teaspoonful of suspension, five times daily. If necessary, a dose of mg two mg tablets or two teaspoonfuls of suspension given twice daily may be considered.
What is acyclovir, and how does it work mechanism of action? Acyclovir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity interferes with viral replication against the herpes viruses, including herpes zovirax 800mg oral 1 and 2 cold sores and genital herpes, varicella -zoster shingles and chickenpox, and Epstein-Barr virus mononucleosis. Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The FDA approved acyclovir in March What are the uses for acyclovir? What are the side effects of acyclovir?
Acyclovir is also sometimes used to prevent outbreaks of zovirax 800mg oral herpes in people who are infected with the virus. Acyclovir comes as a tablet, a capsule, and a suspension liquid to take by mouth. It also comes as a delayed-release buccal tablet to apply to the upper gum of the mouth. The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. The delayed-release buccal tablet is usually applied with a dry finger as a one-time dose within 1 hour after itching, redness, burning or tingling cold sore symptoms begin but before the cold sore appears.
It is used mainly for the treatment of viral infections due to herpes simplex virus types 1 and 2 and varicella-zoster virus herpes zoster and chickenpox. Both initial and recurrent infections can be successfully treated. Prolonged treatment can reduce the incidence of recurrence which is particularly important in immunocompromised patients. However, when prolonged treatment is withdrawn, infections may recur. Aciclovir also improves the healing of herpes zoster lesions and reduces acute pain when given intravenously or by mouth; use to prevent postherpetic neuralgia is controversial.