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It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. Do not start taking bupropion during the 2 weeks after you stop a MAO inhibitor. Wait for 2 weeks after stopping bupropion before you start taking a MAO inhibitor. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe convulsions. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system CNS.

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