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If nocturnal enuresis is left untreated, resolving the problem can become more difficult. A diagnosis of nocturnal enuresis requires careful coordination of both the patient and the family for optimal outcomes and to avoid relapse.
In part 2, placebo patients were randomized to one of the other 4 treatment arms based on assignments predetermined at the initial randomization, to receive active desmopressin melt for between 1 and 6 months until the database for part 1 was locked and treatment was unblinded. Drug: Placebo Oral placebo placed under the participant's tongue, without water, once daily approximately 1 hour before bedtime. Participants continued on this dose in part 2 of the study for between 1 and 6 months until the database for part 1 was locked and treatment was unblinded. Participants will continue on this dose in part 2 of the study for between months until the database for part 1 is locked and treatment is unblinded. Nocturnal void data were recorded in participant diaries.
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The usual dose is 5 mg PO 2—3 times per day. The maximum dose is 5 mg PO 4 times per day.
Nocdurna is a brand-name drug prescribed for nocturia frequent urination at night. Nocdurna contains the active drug desmopressin acetate and belongs to the antidiuretic drug class. Nocdurna is FDA-approved to treat nocturia in adults. With nocturnal polyuria, your kidneys make too much urine at night. Nocdurna is available only as a brand-name medication. Nocdurna contains the active ingredient desmopressin acetate.
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